AJTMH ASTMH MEMBERSHIP INFORMATION: astmh@astmh.org
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


Am. J. Trop. Med. Hyg., 12(3), 1963, pp. 378-382
Copyright © 1963 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Peña-Chavarría, A.
Right arrow Articles by Thompson, P. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Peña-Chavarría, A.
Right arrow Articles by Thompson, P. E.

The Effects of Triclofenol Piperazine in Patients Parasitized by Hookworms, Ascarids, or Trichurids

Antonio Peña-Chavarría, Cecilia Lizano, Kenneth O. Courtney AND Paul E. Thompson
Hospital San Juan de Dios, San José, Costa Rica, and Research Division, Parke, Davis & Company, Ann Arbor, Michigan

Forty hospitalized patients severely infected with two or more types of intestinal nematodes were treated with triclofenol piperazine in a single dose of 50, 60, or 70 mg/kg, or in two 50 mg/kg doses.

Urinalyses, hematologic examinations, and egg counts were made before and after treatment.

The drug was well tolerated, other than moderate gastrointestinal side effects with the higher doses. The drug had good anthelmintic action, as reflected by a great reduction in the number of hookworm and ascarid eggs, a moderate reduction in whipworm eggs, and clinical improvement reflected by increases in hemoglobin and weight.

The 50 or 60 mg/kg dose is recommended for further study.







HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1963 by the American Society of Tropical Medicine and Hygiene.