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Am. J. Trop. Med. Hyg., 12(2), 1963, pp. 249-253
Copyright © 1963 by The American Society of Tropical Medicine and Hygiene

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Penetrance of the Gene for Dieldrin Resistance in Anopheles Albimanus Wiedemann*

Lloyd E. Rozeboom
Laboratories of Medical Entomology, Department of Pathobiology, the Johns Hopkins University, School of Hygiene and Public Health, Baltimore, Maryland

Selection of successive generations of a dieldrin resistant strain of Anopheles albimanus by exposure to dieldrin-impregnated papers resulted in a rapid increase in frequency of the dominant gene for resistance. This gene is estimated to be 100 percent penetrant in the heterozygous and homozygous resistant mosquitoes. In addition to the single dominant gene, there appeared to be also a selection for ancillary genes conferring additional resistance. There was no loss in the frequency of the single dominant gene for resistance in the parent colony after about 3 years of laboratory rearing without selection pressure.


* This work was supported in part by research grants from the National Institutes of Health, USPHS, and the Pan American Health Organization.







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Copyright © 1963 by the American Society of Tropical Medicine and Hygiene.