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Am. J. Trop. Med. Hyg., 11(5), 1962, pp. 678-682
Copyright © 1962 by The American Society of Tropical Medicine and Hygiene

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Isolation of Viruses from Mosquitoes Collected at Lumbo, Mozambique

I. Lumbo Virus, A New Virus Isolated From Aedes (Skusea) Pembaensis Theobald*

R. H. Kokernot{dagger}, B. M. McIntosh, C. Brooke Worth, Tito De Morais{ddagger} AND M. P. Weinbren
Arthropod-borne Virus Research Unit, P. O. Box 1038, Johannesburg , South Africa

Twelve strains of a hitherto unknown virus have been isolated from Aedes (Skusea) pembaensis collected in 1959 and 1960 at Lumbo in northeastern Mozambique. The name proposed for the agent is Lumbo.

Lumbo virus is filterable and withstands lyophilization but is sensitive to sodium desoxycholate. It is pathogenic for adult mice and hamsters by the intracerebral but not the intraperitoneal inoculation route. Vervet monkey, yellow baboon, bushbaby and guinea pig develop an immune response to the virus without showing signs of illness. Viremia was detected on the 3rd and 4th postinoculation days in a vervet monkey. Of 128 human sera collected at Lumbo and Ndumu, northern Natal, in the tropical corridor in southeastern Africa, 16 contained neutralizing antibodies; all of 175 human sera collected in Angola and the Caprivi Strip were negative.


* The studies and observations on which this paper is based were financed jointly by the Institute for Medical Research of Mozambique, the Institute of Tropical Medicine (Portugal), the South African Institute for Medical Research, the Poliomyelitis Research Foundation, the South African Council for Scientific and Industrial Research and The Rockefeller Foundation.


{dagger} Present address: The Rockefeller Foundation, 111 West 50th Street, New York 20.


{ddagger} Institute for Medical Research, Mozambique.






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Copyright © 1962 by the American Society of Tropical Medicine and Hygiene.