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The incidence of skin sensitivity to histoplasmin, tuberculin, and blastomycin in a population of 447 Liberians, predominately working males, was found to be 15.4%, 80.8% and 1.6% respectively.
There was no evidence for cross reaction between any of the antigens used.
Of the histoplasmin reactors 70% were followed by chest x-rays. Of 48 chest films examined only 11 showed pulmonary lesions, and only 9 (18.8%) of these consisted of calcifications. All but one of the positive x-rays were of subjects who were also tuberculin positive, and none of the lesions seen was absolutely typical of histoplasmosis.
* College of Physicians and Surgeons, Columbia University, New York City.
Supported in part by Grant 2E-55 from National Institutes of Health, Public Health Service.
Firestone Health Services, Harbel, Liberia.
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