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Chickens produce antibody in high-titer when injected with serum proteins of other birds. These antisera have little or no cross-reactivity with serum proteins from birds of different orders, but do react in high-titer to closely related bird species.
Absorptions of the antisera with a serum of a closely related species will remove much of the homologous antibody, while absorption with a distantly related serum will not.
* This investigation was supported in part by a research grant (E3028C-2) from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, U.S. Department of Health, Education and Welfare.
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