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Further Studies on the Serological Relationships of Group C Arthropod-Borne Viruses and the Application of these Relationships to Rapid Identification of Types^*

In studies by HI and CF tests of the serological reactions of 200 strains of group C virus, 199 strains reacted similarly to one of the six prototype viruses; examples are given of HI and CF reaction patterns for each type. The one exception, strain H 5546, reacted by HI like Caraparu and by CF like Oriboca and Murutucu.

These serological relationships have suggested a method of combined CF and HI techniques for the rapid identification of new group C isolates. Since 1959, 576 isolates have been identified to type by this method.

^* The studies and observations on which this paper is based were conducted with the support and under the auspices of the Serviço Especial de Saúde Públiea of Brazil and The Rockefeller Foundation.

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