AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 11(1), 1962, pp. 149-154
Copyright © 1962 by The American Society of Tropical Medicine and Hygiene

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Encephalitis on Taiwan*

IV. Human Serology

San-Pin Wang AND J. Thomas Grayston{dagger}
United States Naval Medical Research Unit No. 2, Taipei, Taiwan

The results of serologic tests with Japanese encephalitis virus antigen and sera from humans on Taiwan and adjacent islands are reported. Seventy-one of 72 adult sera from various parts of Taiwan showed neutralizing antibody against JE virus. Neutralizing antibody was found in 32% of 120 sera from 7-year-old children. Tests with sera from the Taipei area show an increasing percentage of neutralizing antibody in children from 1 through 12 years of age. HI antibody tests on these children's serum taken before and after the 1958 encephalitis season showed 4% with fourfold titer rises and a similar percent with falls in titer. The children with antibody rises were 4 to 10 years of age. Similar studies in the nearby Pescadore Islands showed that infection was uncommon in children and that only half of the adults tested had neutralising antibody. A limited interpretation of these results is presented.


* This work has been supported in part by contract Nonr-2121(07) between the Office of Naval Research and the University of Chicago, and in part by funding under Public Law 480, Section 104(c). The opinions and assertions contained herein are those of the authors and are not to be construed as official or reflecting the views of the views of the Navy Department or the Naval Service at large.


{dagger} Present address: Department of Preventive Medicine, University of Washington, Seattle 5, Washington.






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Copyright © 1962 by the American Society of Tropical Medicine and Hygiene.