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Treatment of Tapeworm Infection with Desaspidin, a New Phloroglucinol Derivative Isolated from Finnish Fern^*

The anthelmintic effect of the phloroglucinol derivative desaspidin in the treatment of fish tapeworm (Diphyllobothrium latum) infection was studied. The drug was used in doses of 200 and 400 mg. Thirty grams of castor oil emulsion was given as a purgative. The 200 mg dose of desaspidin was effective. A total of 2,368 persons received treatment. A significant side effect was observed in only one subject.

^* The investigation was performed in 1959–1960 during the Finnish Red Cross campaign against the tapeworm scourge in Northern Karelia with the permission of the State Medical Board of Finland. The desaspidin was supplied by the drug manufacturer, Medica Ltd., Helsinki, Finland.