AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 1(5), 1952, pp. 852
Copyright © 1952 by The American Society of Tropical Medicine and Hygiene

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Failure of Aureomycin in the Treatment of Schistosomiasis1

John A. Hightower2 AND Preston M. Bauman
Tropical Research Medical Laboratory, San Juan, Puerto Rico and the Army Medical Service Graduate School, Washington, D. C.

Fourteen cases of schistosomiasis were treated with aureomycin at the Santa Ana Clinic, Santurce, Puerto Rico. All patients were from 17 to 43 years of age except for one boy aged 8. All but the boy were discharging Schistosoma mansoni in the feces and the diagnosis was confirmed in 12 instances by rectal biopsy. The 8 year old boy was known to have had active schistosomiasis 2 years before and had been losing weight for several months along with a progressive enlargement of the abdomen. Physical examination revealed markedly enlarged liver and spleen. None of the patients were incapacitated at the time of treatment but 5 were underweight or anemic and one had a mild arteriosclerosis. All reported one or more of the following symptoms: epigastric pain and burning, weakness, dizziness, headache, diarrhea or slight difficulty of vision. Four of the patients had previously been treated with Fuadin and had subsequently relapsed.


1 Acknowledgement is made of the cooperation of the Bayamon District Medical and Pediatrics Service and the assistance of Captain William Jahnes and Dr. Ross L. Gauld.


2 Captain, M.C.







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Copyright © 1952 by the American Society of Tropical Medicine and Hygiene.