AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 1(3), 1952, pp. 417-428
Copyright © 1952 by The American Society of Tropical Medicine and Hygiene

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The Experimental Infection of Macaca Mulatta with Human Strains of Entamoeba Histolytica1

Max J. Miller2
Institute of Parasitology, McGill University, Macdonald College, P. Q., Canada, and School of Tropical Medicine, Calcutta, India

The studies of Dobell (1931), Kessel (1928), and others established the fact that the "histolytica-like" amebae found in monkeys are identical with E. histolytica in man. While it has been shown by many investigators that this parasite can be transmitted to a wide variety of hosts, in none of these can the infection be considered a normal one. Thus, dogs, kittens, rats, pigs, rabbits, guinea pigs and even chicks have been infected experimentally with E. histolytica. But in such cases infection is usually achieved only under special conditions. Also, the regular production of cysts is rarely seen, and it seems logical to assume that cyst-production here is good evidence of a normal host-parasite relationship For a proper understanding of the host-parasite relationships of E. histolytica the parasite must be studied in its normal host.


1 Financial assistance for this work was received from the National Research Council of Canada.


2 Associate Professor of Parasitology and Research Assistant.







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Copyright © 1952 by the American Society of Tropical Medicine and Hygiene.