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Am. J. Trop. Med. Hyg., 1(1), 1952, pp. 59-65
Copyright © 1952 by The American Society of Tropical Medicine and Hygiene

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Adaptation of Dengue Virus to the Hamster

Gordon Meiklejohn, Beatrice England AND Edwin H. Lennette
Viral and Rickettsial Disease Laboratory, California State Department of Public Health1

By serial intracerebral passages, the New Guinea C and Hawaiian strains of dengue virus were adapted to growth in hamsters of 2–5 days of age.

Dengue virus should no longer be described, without qualification, as non-pathogenic for the hamster.

Additional data are presented showing that the New Guinea C and Hawaiian strains represent 2 different immunologic types of dengue virus.


1 1392 University Avenue, Berkeley 2, California.






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Copyright © 1952 by the American Society of Tropical Medicine and Hygiene.